Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596901 | 0.92 | PDE5A (0.80) | PDE5APDE2A | |
| SCHEMBL6597558 | 0.90 | PDE5A (0.76) | PDE5APDE2A | |
| SCHEMBL6598334 | 0.89 | PDE5A (0.84) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6593977 | 0.89 | PDE5A (1.00) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6595313 | 0.89 | PDE5A (1.00) | PDE5APDE2A | |
| Hydrochloric Acid SCHEMBL6596617 | 0.88 | PDE5A (0.84) | PDE5APDE2A | |
| SCHEMBL6597885 | 0.88 | PDE5A (0.84) | PDE5APDE2A | |
| SCHEMBL6595385 | 0.86 | PDE5A (0.81) | PDE5APDE2A | |
| SCHEMBL6593827 | 0.86 | PDE5A (0.90) | PDE5APDE2A | |
| SCHEMBL27467175 | 0.85 | PDE5A (0.78) | PDE5APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218392-B1 | FOR THERAPY AND PROPHYLAXIS OF ISCHEMIC HEART DISEASES SUCH AS ANGINA PECTORIS, MYOCARDIAL INFARCT AND CHRONIC AND ACUTE CARDIAC FAILURE, PULMONARY HYPERTENSION, ARTERIOSCLEROSIS AND BRONCHIAL ASTHMA | EISAI CO., LTD. (JP) | 2001-04-17 | — | — | US | claimed |
| EP-0722936-B1 | FUSED PYRIDAZINE COMPOUND | EISAI CO LTD (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6218392-B1 | FOR THERAPY AND PROPHYLAXIS OF ISCHEMIC HEART DISEASES SUCH AS ANGINA PECTORIS, MYOCARDIAL INFARCT AND CHRONIC AND ACUTE CARDIAC FAILURE, PULMONARY HYPERTENSION, ARTERIOSCLEROSIS AND BRONCHIAL ASTHMA | EISAI CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| US-5849741-A | Fused pyridazine compounds | EISAI CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0722936-A1 | FUSED PYRIDAZINE COMPOUND | Eisai Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |