SCHEMBL6595279

SCHEMBL6595279

CC(C)C[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)N[C@H]1CCN(Cc2ccc(OCCCN(C)C)cc2)C1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7403975 0.88 DRD4 (0.66) UTS2R
SCHEMBL7408349 0.87 UTS2R (0.66) UTS2R
SCHEMBL7412384 0.87 UTS2R (0.64) UTS2R
SCHEMBL7407746 0.87 UTS2R (0.64) UTS2R
SCHEMBL7412018 0.87 UTS2R (0.64) UTS2R
SCHEMBL7411042 0.87 UTS2R (0.62) UTS2R
SCHEMBL7409331 0.86 UTS2R (0.64) UTS2R
SCHEMBL7411577 0.86 DRD4 (0.64) UTS2R
SCHEMBL7409368 0.85 UTS2R (0.61) UTS2R
SCHEMBL7412664 0.85 UTS2R (0.61) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1246619-B1 UROTENSIN-II RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORP (US) 2004-10-20 EP claimed