Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543491 | 0.91 | PDE5A (0.45) | PDE5AGAAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27468605 | 0.86 | PDE5A (0.51) | PDE5AALDH1A1SMN1; SMN2 | |
| SCHEMBL27466743 | 0.83 | PDE5A (0.46) | PDE5AGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL27466739 | 0.83 | PDE5A (0.46) | PDE5AGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL27548033 | 0.82 | PDE5A (0.39) | PDE5AALDH1A1SMN1; SMN2KDM4ETHRB | |
| SCHEMBL27467176 | 0.81 | PDE4A (0.48) | PDE5AHPGD | |
| SCHEMBL27451249 | 0.81 | PDE5A (0.51) | PDE5AALDH1A1SMN1; SMN2KDM4ETHRB | |
| SCHEMBL27466247 | 0.80 | PDE5A (0.37) | PDE5AALDH1A1SMN1; SMN2KDM4ETHRB | |
| SCHEMBL27548037 | 0.78 | PDE5A (0.55) | PDE5A | |
| SCHEMBL27503954 | 0.77 | PDE5A (0.44) | PDE5AGAAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151136-C | Condensed pyridazine compound | ������������ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| EP-0722936-B1 | FUSED PYRIDAZINE COMPOUND | EISAI CO LTD (JP) | 2004-05-19 | — | — | EP | disclosed |
| CN-1135210-A | Fused pyridazine compound | EISAI CO LTD (JP) | 1996-11-06 | — | — | CN | disclosed |