Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14676453 | 1.00 | ATM (0.43) | ATMPOLBMAPT | |
| SCHEMBL28764312 | 1.00 | ATM (0.43) | ATMPOLBMAPT | |
| SCHEMBL28689770 | 0.92 | ATM (0.40) | ATMPOLBMAPT | |
| SCHEMBL6596130 | 0.92 | ATM (0.40) | ATMPOLBMAPT | |
| SCHEMBL6608359 | 0.91 | ATM (0.39) | ATMPOLBMAPT | |
| SCHEMBL6603982 | 0.91 | ATM (0.39) | ATMPOLBMAPT | |
| SCHEMBL16472458 | 0.78 | POLB (0.34) | POLBMAPT | |
| SCHEMBL19449172 | 0.78 | POLB (0.34) | POLBMAPT | |
| SCHEMBL29117209 | 0.77 | ATM (0.35) | ATMMAPT | |
| SCHEMBL15536942 | 0.77 | ATM (0.35) | ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156803-A4 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1156803-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000047207-A1 | LACTAM INHIBITORS OF FXa AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-17 | — | — | WO | disclosed |