Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TNF | P01375 | 3/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593619 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6597390 | 0.87 | KDM4E (0.65) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6597386 | 0.87 | KDM4E (0.65) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6597677 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6597680 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6597345 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6594246 | 0.81 | TNF (0.74) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6594250 | 0.81 | TNF (0.74) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6594489 | 0.78 | TNF (0.64) | KDM4EALDH1A1TNFNOD1RAB9A | |
| SCHEMBL6594487 | 0.78 | TNF (0.64) | KDM4EALDH1A1TNFNOD1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | claimed |
| EP-1389461-A1 | Pyrimidones with antiviral properties | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |