Dimethylamine

Dimethylamine

SCHEMBL659646

CC1CCC(C)CC1.CNC

nearest known ligand 0.38

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT1 Q99873 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
EPHX1 P07099 1/20 0.36
ESR2 Q92731 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL8638912 0.95
Dimethylamine SCHEMBL28018605 0.91
SCHEMBL9263434 0.85 ESR2 (0.36) CARM1PRMT6PRMT1PRMT8EPHX1
SCHEMBL598344 0.85
SCHEMBL135763 0.85
SCHEMBL11469288 0.85
SCHEMBL1492417 0.85
Methylcyclopentane SCHEMBL10358842 0.84
Dimethylamine SCHEMBL28284740 0.81 EPHX1 (0.42) CARM1PRMT6PRMT1PRMT8EPHX1
Dimethylamine SCHEMBL28285682 0.81 EPHX1 (0.42) CARM1PRMT6PRMT1PRMT8EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215762-A1 Siloxane polymer containing tethered levofloxacin NDSU RESEARCH FOUNDATION 2009-08-27 US claimed
US-8283432-B2 Siloxane polymer containing tethered fluoroquinolone NDSU RESEARCH FOUNDATION (US) 2012-10-09 US disclosed
US-8278400-B2 Antifouling materials containing cationic polysiloxanes NDSU RESEARCH FOUNDATION (US) 2012-10-02 US disclosed
US-20120046313-A1 SILOXANE POLYMER CONTAINING TETHERED FLUOROQUINOLONE NDSU RESEARCH FOUNDATION 2012-02-23 US disclosed
US-20100204399-A1 ANTIFOULING MATERIALS CONTAINING CATIONIC POLYSILOXANES NDSU RESEARCH FOUNDATION 2010-08-12 US disclosed
US-7771833-B2 Anti-fouling materials containing cationic polysiloxanes NDSU RESEARCH FOUNDATION (US) 2010-08-10 US disclosed
US-20090215762-A1 Siloxane polymer containing tethered levofloxacin NDSU RESEARCH FOUNDATION 2009-08-27 US disclosed
US-20070042199-A1 Anti-fouling materials containing cationic polysiloxanes NDSU RESEARCH FOUNDATION 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046313-A1 SILOXANE POLYMER CONTAINING TETHERED FLUOROQUINOLONE QARS1, SEPTIN7, SMCHD1 CARM1 4543/4885PRMT6 2277/4885PRMT1 3367/4885
US-20090215762-A1 Siloxane polymer containing tethered levofloxacin PUF60, QARS1, SEPTIN7 CARM1 3304/4885PRMT6 1082/4885PRMT1 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.