Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.64 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596398 | 0.88 | F2 (0.84) | F2ESR1ESR2 | |
| SCHEMBL7621953 | 0.87 | F2 (0.61) | F2ESR1ESR2PAX8 | |
| Hydrochloric Acid SCHEMBL7673315 | 0.86 | F2 (0.60) | F2ESR1ESR2PAX8 | |
| SCHEMBL6598745 | 0.82 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL7986006 | 0.79 | F2 (0.89) | F2ESR1ESR2 | |
| SCHEMBL6594996 | 0.78 | F2 (1.00) | F2ESR1ESR2 | |
| SCHEMBL6594625 | 0.78 | F2 (0.82) | F2ESR1ESR2 | |
| SCHEMBL7618884 | 0.78 | F2 (0.59) | F2ESR1ESR2 | |
| SCHEMBL7452488 | 0.77 | F2 (1.00) | F2ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7671638 | 0.77 | F2 (0.58) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |