Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.59 |
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595900 | 1.00 | F2 (0.59) | F2ESR1ESR2ENPP1LTA4H | |
| SCHEMBL6597446 | 1.00 | F2 (0.59) | F2ESR1ESR2ENPP1LTA4H | |
| SCHEMBL6595905 | 1.00 | F2 (0.59) | F2ESR1ESR2ENPP1LTA4H | |
| SCHEMBL6595903 | 1.00 | F2 (0.59) | F2ESR1ESR2ENPP1LTA4H | |
| SCHEMBL6598518 | 0.93 | F2 (0.58) | F2ESR1ESR2LTA4H | |
| SCHEMBL6598516 | 0.93 | F2 (0.58) | F2ESR1ESR2LTA4H | |
| SCHEMBL6598511 | 0.93 | F2 (0.58) | F2ESR1ESR2LTA4H | |
| SCHEMBL6596972 | 0.91 | F2 (0.72) | F2ESR1ESR2 | |
| SCHEMBL6596449 | 0.91 | F2 (0.72) | F2ESR1ESR2 | |
| SCHEMBL6596444 | 0.91 | F2 (0.72) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |