SCHEMBL6598080

SCHEMBL6598080

N[C@@H](CC(=O)NCCCOc1ccc(-c2sc3ccccc3c2Cc2ccc(OCCN3CCCC3)cc2)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2 P00734 9/20 0.52
ITGA4 P13612 1/20 0.51
ESR1 P03372 9/20 0.51
ESR2 Q92731 9/20 0.51
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6598088 1.00 F2 (0.52) F2ITGA4ESR1ESR2ACHE
SCHEMBL7772284 0.88 F2 (0.58) F2ITGA4ESR1ESR2
Hydrochloric Acid SCHEMBL7991848 0.87 F2 (0.51) F2ITGA4ESR1ESR2
Hydrochloric Acid SCHEMBL7991851 0.87 F2 (0.51) F2ITGA4ESR1ESR2
Hydrochloric Acid SCHEMBL7989132 0.85 ESR1 (0.56) F2ITGA4ESR1ESR2
Hydrochloric Acid SCHEMBL7989122 0.85 ESR1 (0.56) F2ITGA4ESR1ESR2
Hydrochloric Acid SCHEMBL7989938 0.84 F2 (0.53) F2ITGA4ESR1ESR2
Hydrochloric Acid SCHEMBL7989932 0.84 F2 (0.53) F2ITGA4ESR1ESR2
Oxalic Acid SCHEMBL6174272 0.84 F2 (0.57) F2ITGA4ESR1ESR2
SCHEMBL6596774 0.83 F2 (0.47) F2ITGA4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0980366-B1 ANTITHROMBOTIC AGENTS LILLY CO ELI (US) 2004-06-09 EP disclosed
US-6271227-B1 ANTICOAGULANTS ELI LILLY AND COMPANY 2001-08-07 US disclosed