Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599375 | 0.91 | FNTA (0.45) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6599572 | 0.89 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6601438 | 0.87 | FNTA (0.47) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6599696 | 0.81 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6607626 | 0.81 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6598883 | 0.81 | FNTA (0.47) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6599733 | 0.81 | FNTA (0.48) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6600663 | 0.78 | KDM4E (0.44) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6600318 | 0.75 | FNTA (0.58) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL4955195 | 0.75 | FNTA (0.60) | FNTAFNTBPGGT1BCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |