Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6598254 | 1.00 | FFAR1 (0.48) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6594366 | 0.90 | PPARG (0.52) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6595347 | 0.90 | PPARG (0.52) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6597150 | 0.87 | FFAR1 (0.46) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6596770 | 0.87 | FFAR1 (0.46) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6597418 | 0.80 | HPGD (0.54) | HPGD | |
| SCHEMBL6598314 | 0.80 | HPGD (0.54) | HPGD | |
| SCHEMBL6596984 | 0.80 | FFAR1 (0.46) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6597405 | 0.80 | FFAR1 (0.46) | FFAR1PPARGPPARAMEN1ALDH1A1 | |
| SCHEMBL6597590 | 0.79 | HTR2C (0.41) | ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981526-B1 | NOVEL ANTIDIABETIC COMPOUNDS HAVING HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2004-02-25 | — | — | EP | claimed |