Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188377 | 0.96 | USP30 (0.60) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3834612 | 0.96 | USP30 (0.60) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12567215 | 0.96 | USP30 (0.60) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17387921 | 0.83 | NPC1 (0.59) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13379469 | 0.83 | NPC1 (0.59) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15972262 | 0.83 | NPC1 (0.59) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12567167 | 0.83 | NPC1 (0.58) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13379461 | 0.82 | NPC1 (0.58) | USP30NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9105606 | 0.82 | NPC1 (0.57) | USP30NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL9105614 | 0.82 | NPC1 (0.57) | USP30NPC1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | Warner-Lambert Company LLC (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003045912-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2003-06-05 | — | — | WO | disclosed |