Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602675 | 0.82 | MEN1 (0.43) | MEN1KMT2ARXFP1MAPTHTT | |
| SCHEMBL6599085 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL6599300 | 0.79 | KDM4E (0.47) | KMT2AL3MBTL1KDM4EALDH1A1GLA | |
| SCHEMBL30344464 | 0.77 | MEN1 (0.65) | MEN1KMT2ARXFP1AKR1C3AKR1C2 | |
| SCHEMBL1228020 | 0.77 | MEN1 (0.65) | MEN1KMT2ARXFP1AKR1C3AKR1C2 | |
| SCHEMBL29434773 | 0.77 | CYP2A6 (0.48) | MEN1KMT2ARXFP1MAPTNPSR1 | |
| SCHEMBL31491192 | 0.70 | MEN1 (0.60) | MEN1KMT2ARXFP1AKR1C3AKR1C2 | |
| SCHEMBL29418249 | 0.70 | KDM4E (0.46) | MAPTNPSR1TDP1L3MBTL1KDM4E | |
| SCHEMBL13719437 | 0.70 | MEN1 (0.60) | MEN1KMT2ARXFP1AKR1C3AKR1C2 | |
| SCHEMBL17751069 | 0.70 | MEN1 (0.63) | MEN1KMT2ARXFP1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| CN-1151148-C | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LGCI��ʽ���� | 2004-05-26 | — | — | CN | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |
| CN-1346353-A | farnesyl transferase inhibitor with pyrrole structure and preparation method thereof | LG CHEMICAL LTD (KR) | 2002-04-24 | — | — | CN | disclosed |