Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401497 | 0.84 | EPHX1 (0.46) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL13947314 | 0.84 | EPHX1 (0.46) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL10886661 | 0.82 | EPHX1 (0.52) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL2773744 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL29835069 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL23015007 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL4897786 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL2772887 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL11448367 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 | |
| SCHEMBL7671118 | 0.81 | EPHX1 (0.55) | EPHX1SPHK1THRBHSD17B10CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373196-A2 | SULFOXIDES OR SULFONES GRAFTED ONTO POLYMERS | Ciba SC Holding AG (CH) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081432-A2 | SULFOXIDES OR SULFONES GRAFTED ONTO POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-17 | — | — | WO | disclosed |