Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 20/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599225 | 0.96 | UTS2R (0.83) | UTS2RHTR1ACYP2D6DRD2HTR1D | |
| SCHEMBL6597367 | 0.90 | UTS2R (0.72) | UTS2RHTR1ACYP2D6DRD2HTR1D | |
| SCHEMBL6600179 | 0.90 | UTS2R (0.70) | UTS2R | |
| SCHEMBL6596228 | 0.84 | UTS2R (0.68) | UTS2R | |
| SCHEMBL6599748 | 0.83 | UTS2R (0.62) | UTS2R | |
| SCHEMBL6597841 | 0.81 | UTS2R (0.65) | UTS2RHTR1ACYP2D6DRD2HTR1D | |
| SCHEMBL6596760 | 0.76 | UTS2R (0.68) | UTS2R | |
| SCHEMBL6595561 | 0.76 | UTS2R (0.82) | UTS2R | |
| SCHEMBL6597273 | 0.76 | UTS2R (0.68) | UTS2RHTR1ACYP2D6DRD2HTR1D | |
| SCHEMBL6597839 | 0.72 | UTS2R (0.62) | UTS2RHTR1ACYP2D6DRD2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246619-B1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | claimed |