Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.48 |
| ▸ | FNTB | P49356 | 5/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601984 | 0.79 | KDM4E (0.47) | KDM4EMAPK1L3MBTL1CYP3A4CMA1 | |
| SCHEMBL6599662 | 0.78 | CYP11B1 (0.52) | FNTAFNTBPGGT1BKDM4EMAPK1 | |
| SCHEMBL13160969 | 0.78 | CYP11B1 (0.50) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL6602509 | 0.77 | FNTA (0.49) | FNTAFNTBPGGT1BKDM4EMAPK1 | |
| SCHEMBL3628808 | 0.76 | CYP11B1 (0.60) | FNTAFNTBPGGT1B | |
| SCHEMBL6598800 | 0.71 | PDE5A (0.40) | FNTAFNTBPGGT1BKDM4EMAPK1 | |
| SCHEMBL27559433 | 0.71 | KDM4E (0.49) | KDM4EMAPK1L3MBTL1CMA1MEN1 | |
| SCHEMBL1106692 | 0.70 | BACE1 (0.33) | FNTAFNTBPGGT1B | |
| SCHEMBL1097299 | 0.70 | CYP19A1 (0.42) | FNTAFNTBPGGT1BMAPT | |
| SCHEMBL27580269 | 0.69 | TSHR (0.62) | FNTAFNTBPGGT1BKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |