Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151267 | 0.90 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631393 | 0.89 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL4632397 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151368 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151276 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4663316 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631551 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7231363 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631818 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL27456267 | 0.81 | EDNRA (0.74) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594021-A | VASOCONSTRICTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-01-14 | — | — | US | claimed |
| CN-1636994-B | Process of preparing alkali metal salys of hydrophobic sulfonamides and alkali metal salt produced thereby | ENCYSIVE PHARMACEUTICALS INC | 2010-05-12 | — | — | CN | disclosed |
| CN-100558724-C | Adjust active sulphonamide of endothelium peptide and derivative thereof | ANSEHIV PHARMACEUTICAL CORP (US) | 2009-11-11 | — | — | CN | disclosed |
| CN-1215069-C | Sulfonamides and derivatives thereof that modulate the activity of endothelin | ENCYSIVE PHARMACEUTICALS INC (US) | 2005-08-17 | — | — | CN | disclosed |
| CN-1636994-A | Process of preparing alkali metal salys of hydrophobic sulfonamides and alkali metal salt produced thereby | ENCYSIVE PHARMACEUTICALS INC (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1179961-C | Sulfonamides for the treatment of endothelin mediated diseases | ��ɪϣ����ҩ��˾ | 2004-12-15 | — | — | CN | disclosed |
| CN-1530366-A | Sulphonic acid amide for regulating bast peptide activity and derivative thereof | ��ɪϣ����ҩ��˾ | 2004-09-22 | — | — | CN | disclosed |
| EP-0946552-B1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | ENCYSIVE PHARMACEUTICALS INC (US) | 2004-07-07 | — | — | EP | disclosed |
| CN-1130355-C | Thienyl-, Furyl-, Pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORP (US) | 2003-12-10 | — | — | CN | disclosed |
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1231664-A | Sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORP (US) | 1999-10-13 | — | — | CN | disclosed |
| CN-1184470-A | Thienyl-, Furyl-, Pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORP (US) | 1998-06-10 | — | — | CN | disclosed |