Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631820 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7224061 | 0.84 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL4663316 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631879 | 0.83 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL4632397 | 0.82 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631366 | 0.82 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL6151615 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631365 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL4631822 | 0.81 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL4631503 | 0.80 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594021-A | VASOCONSTRICTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1997-01-14 | — | — | US | claimed |
| EP-0946552-B1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | ENCYSIVE PHARMACEUTICALS INC (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1048657-A1 | Thienyl-, furyl-, pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2000-11-02 | — | — | EP | disclosed |