Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.67 |
| ▸ | CDK4 | P11802 | 6/20 | 0.67 |
| ▸ | CDK1 | P06493 | 2/20 | 0.59 |
| ▸ | IKBKB | O14920 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817051 | 0.88 | CDK2 (0.72) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL6106428 | 0.86 | CDK2 (0.90) | CDK2CDK4CDK1 | |
| SCHEMBL6599765 | 0.84 | CDK2 (0.57) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4820462 | 0.82 | CDK2 (0.80) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL6601934 | 0.81 | CCNT1 (0.61) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL6595584 | 0.81 | CDK2 (0.78) | CDK2CDK4CDK1 | |
| SCHEMBL5092316 | 0.80 | CDK2 (1.00) | CDK2CDK4CDK1 | |
| SCHEMBL6593918 | 0.80 | CDK2 (0.90) | CDK2CDK4CDK1 | |
| SCHEMBL4825298 | 0.78 | CDK2 (0.71) | CDK2CDK4CDK1IKBKB | |
| SCHEMBL4821591 | 0.77 | CDK2 (0.72) | CDK2CDK4CDK1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485374-A1 | PYRIMIDINE COMPOUNDS | AstraZeneca AB (SE) | 2004-12-15 | — | — | EP | claimed |
| WO-2003076433-A1 | PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-09-18 | — | — | WO | claimed |