Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017095 | 1.00 | TACR1 (0.59) | TACR1SIGMAR1CYP3A4PTAFR | |
| SCHEMBL4018869 | 1.00 | TACR1 (0.59) | TACR1SIGMAR1CYP3A4PTAFR | |
| SCHEMBL4014185 | 1.00 | TACR1 (0.59) | TACR1SIGMAR1CYP3A4PTAFR | |
| SCHEMBL4016202 | 1.00 | TACR1 (0.59) | TACR1SIGMAR1CYP3A4PTAFR | |
| Hydrochloric Acid SCHEMBL4018154 | 0.99 | TACR1 (0.58) | TACR1SIGMAR1CYP3A4PTAFR | |
| Hydrochloric Acid SCHEMBL4015924 | 0.99 | TACR1 (0.58) | TACR1SIGMAR1CYP3A4PTAFR | |
| SCHEMBL3239318 | 0.86 | TACR1 (0.60) | TACR1SIGMAR1CYP3A4PTAFR | |
| SCHEMBL5497810 | 0.84 | TACR1 (0.74) | TACR1SIGMAR1CYP3A4PTAFR | |
| Hydrochloric Acid SCHEMBL5619491 | 0.83 | TACR1 (0.55) | TACR1SIGMAR1CYP3A4PTAFR | |
| Hydrochloric Acid SCHEMBL5619955 | 0.83 | TACR1 (0.55) | TACR1SIGMAR1CYP3A4PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472222-A1 | PIPERIDYLCARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF TACHYKINIM-MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003066589-A1 | PIPERIDYLCARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF TACHYKINIM-MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-08-14 | — | — | WO | disclosed |