Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.52 |
| ▸ | FNTB | P49356 | 9/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599878 | 0.88 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6983944 | 0.86 | FNTA (0.65) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6598311 | 0.83 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6600323 | 0.79 | FNTA (0.76) | FNTAFNTBPGGT1BCYP3A4ALDH1A1 | |
| SCHEMBL6599549 | 0.78 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6972928 | 0.77 | FNTA (0.71) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6972967 | 0.75 | FNTA (0.75) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6982585 | 0.75 | FNTA (0.67) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL6982723 | 0.75 | FNTA (0.67) | FNTAFNTBPGGT1BCYP3A4KDM4E | |
| SCHEMBL7545329 | 0.75 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | claimed |