Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.44 |
| ▸ | FNTB | P49356 | 13/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6610933 | 0.91 | FNTA (0.48) | FNTAFNTBPGGT1BCYP3A4POLB | |
| SCHEMBL6599647 | 0.91 | FNTA (0.50) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6608400 | 0.87 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4POLB | |
| SCHEMBL6599584 | 0.87 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6605790 | 0.87 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6609116 | 0.86 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6598793 | 0.85 | FNTA (0.47) | FNTAFNTBPGGT1BCYP3A4POLB | |
| SCHEMBL6599149 | 0.84 | FNTA (0.57) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6602758 | 0.84 | FNTA (0.46) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6599130 | 0.83 | FNTA (0.52) | FNTAFNTBPGGT1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | claimed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | claimed |
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |
| EP-1169320-A4 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2002-10-30 | — | — | EP | disclosed |
| EP-1169320-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG Chem Investment, Ltd. (KR) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000064891-A1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD. (KR) | 2000-11-02 | — | — | WO | disclosed |