Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | UGCG | Q16739 | 2/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599808 | 0.87 | MEN1 (0.40) | MEN1KMT2ATEAD3CYP1A2CYP2D6 | |
| SCHEMBL6597615 | 0.74 | CYP11B1 (0.47) | MEN1KMT2ATEAD3GBA1UGCG | |
| SCHEMBL6599567 | 0.72 | CYP1A2 (0.34) | MEN1KMT2ATEAD3CYP1A2CYP2D6 | |
| SCHEMBL23115952 | 0.70 | MEN1 (0.48) | ATP4AATP4BMEN1KMT2ATEAD3 | |
| SCHEMBL6597617 | 0.68 | MEN1 (0.41) | MEN1KMT2ATEAD3GBA1UGCG | |
| SCHEMBL15284036 | 0.68 | MEN1 (0.49) | MEN1KMT2ATEAD3GBA1UGCG | |
| SCHEMBL345616 | 0.67 | TSHR (0.58) | TEAD3GBA1UGCGGBA2L3MBTL1 | |
| SCHEMBL7479206 | 0.67 | HRH3 (0.44) | ATP4AATP4BL3MBTL1TDP1LMNA | |
| SCHEMBL8621469 | 0.66 | TSHR (0.70) | TEAD3L3MBTL1TDP1HRH4HRH3 | |
| SCHEMBL2640223 | 0.66 | TSHR (0.70) | GBA1UGCGGBA2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |