Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600338 | 0.91 | CYP3A4 (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6352862 | 0.89 | TUBB1 (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6836554 | 0.87 | CYP3A4 (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6603478 | 0.86 | TUBB1 (0.51) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6832433 | 0.86 | CYP3A4 (0.39) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6600203 | 0.85 | MAPT (0.39) | CYP3A4CYP1A2GAATDP1ALDH1A1 | |
| SCHEMBL6603484 | 0.84 | TUBB1 (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6604342 | 0.83 | TUBB1 (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6356058 | 0.82 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6356166 | 0.81 | TUBB1 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453790-A2 | 1,3-DIARYLPROP-2-EN-1-ONES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | Aventis Pharma S.A. (FR) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048106-A2 | 1,3-DIARYLPROP-2-EN-1-ONES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2003-06-12 | — | — | WO | disclosed |