⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395510 | 1.00 | — | — | |
| SCHEMBL5378661 | 1.00 | — | — | |
| SCHEMBL28932232 | 0.93 | PARP10 (0.35) | — | |
| SCHEMBL31026715 | 0.91 | EPHX1 (0.34) | — | |
| SCHEMBL8693124 | 0.86 | — | — | |
| SCHEMBL6908462 | 0.82 | POLB (0.34) | — | |
| SCHEMBL2988371 | 0.81 | — | — | |
| SCHEMBL242415 | 0.79 | — | — | |
| SCHEMBL14398568 | 0.79 | — | — | |
| SCHEMBL28000893 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | claimed |
| CN-117263760-B | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2025-07-25 | — | — | CN | disclosed |
| CN-117263760-B | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2025-07-25 | — | — | CN | disclosed |
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-110066282-B | Pyrazolopyrimidinone compound and preparation method and application thereof | 南开大学 | 2020-07-10 | — | — | CN | disclosed |
| CN-106689188-B | Composition pesticide, microcapsule suspension seed-coating agent and preparation method thereof | PLANT PROTECTION AND QUALITY & SAFETY OF AGRICULTURAL PRODUCTS INSTITUTE, ANHUI ACADEMY OF AGRICULTURAL SCIENCES (CN) | 2019-11-01 | — | — | CN | disclosed |
| CN-106689188-A | Pesticide composition, and micro-capsule suspended seed coating agent and preparation method thereof | 安徽省农业科学院植物保护与农产品质量安全研究所 | 2017-05-24 | — | — | CN | disclosed |
| US-20120315686-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2012-12-13 | — | — | US | disclosed |
| EP-1409466-A2 | HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS | AGOURON PHARMACEUTICALS, INC. (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002100844-A2 | HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME, THEIR PHARMACEUTICAL USES AND MATERIALS FOR THEIR SYNTHESIS | AGOURON PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-4326925-A | BY VACUUM DISTILLATION | SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) | 1982-04-27 | — | — | US | disclosed |
| US-4314940-A | DECOMPOSITION OF AMIDE IMPURITIES BY TREATING WITH A HYDROXY-CONTAINING COMPOUND | SNIA VISCOSA SOCIETA' NAZIONALE INDUSTRIA APPLICAZIONI VISCOSA S.P.A. (IT) | 1982-02-09 | — | — | US | disclosed |
| US-4293494-A | Method for the purification of raw caprolactam which contains amides and other by-products | SNIA VISCOSA S.P.A. (IT) | 1981-10-06 | — | — | US | disclosed |
| US-4035512-A | Aminotetralols | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | disclosed |