Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.57 |
| ▸ | FNTB | P49356 | 7/20 | 0.57 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600318 | 0.92 | FNTA (0.58) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL4955195 | 0.88 | FNTA (0.60) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6599696 | 0.87 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6607626 | 0.84 | FNTA (0.55) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6977268 | 0.80 | FNTA (0.59) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6599572 | 0.79 | FNTA (0.49) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6598883 | 0.78 | FNTA (0.47) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6601438 | 0.78 | FNTA (0.47) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6599733 | 0.77 | FNTA (0.48) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL6599997 | 0.76 | FNTA (0.75) | FNTAFNTBPGGT1BCYP3A4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | claimed |
| EP-1169320-B1 | FARNESYL TRANSFERASE INHIBITORS HAVING A PYRROLE STRUCTURE AND PROCESS FOR PREPARATION THEREOF | LG CHEM INVESTMENT LTD (KR) | 2004-09-22 | — | — | EP | disclosed |
| US-6511978-B1 | For treating cancer, restenosis, atherosclerosis or viral infections | LG LIFE SCIENCES, LTD. (KR) | 2003-01-28 | — | — | US | disclosed |