Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278006 | 1.00 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6278009 | 1.00 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6281145 | 0.91 | ADRB3 (0.47) | ADRB3ADRB1ADRB2FFAR4 | |
| SCHEMBL6281148 | 0.91 | ADRB3 (0.47) | ADRB3ADRB1ADRB2FFAR4 | |
| SCHEMBL6285889 | 0.87 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6285896 | 0.87 | ADRB3 (0.44) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6284130 | 0.84 | ADRB3 (0.49) | ADRB3ADRB1ADRB2FFAR4 | |
| SCHEMBL6284145 | 0.84 | ADRB3 (0.49) | ADRB3ADRB1ADRB2FFAR4 | |
| SCHEMBL6284190 | 0.84 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6284175 | 0.84 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389202-A1 | 2,6-SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | Bayer Pharmaceuticals Corporation (US) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002085891-A1 | 2,6-SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER PHARMACEUTICALS CORPORATION (US) | 2002-10-31 | — | — | WO | disclosed |