Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.53 |
| ▸ | CNR2 | P34972 | 7/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158491 | 0.91 | CNR1 (0.48) | CNR1CNR2CHRM1TAS1R3TAS1R1 | |
| SCHEMBL7158484 | 0.91 | CNR1 (0.48) | CNR1CNR2CHRM1TAS1R3TAS1R1 | |
| SCHEMBL7158488 | 0.91 | CNR1 (0.48) | CNR1CNR2CHRM1TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL6614304 | 0.77 | CNR1 (0.55) | CNR1CNR2CHRNA7 | |
| SCHEMBL6613358 | 0.75 | CNR1 (0.48) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL6614542 | 0.74 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL6600466 | 0.74 | CNR1 (0.49) | CNR1CNR2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13574377 | 0.72 | CHRNA7 (0.61) | CHRNA7 | |
| SCHEMBL13717376 | 0.70 | CNR1 (0.71) | CNR1CNR2CHRM1TAS1R3TAS1R1 | |
| SCHEMBL13717145 | 0.70 | CNR1 (0.79) | CNR1CNR2CHRM1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432679-A1 | PREPARATION AND USE OF PYRROLE DERIVATIVES FOR TREATING OBESITY | Bayer Pharmaceuticals Corporation (US) | 2004-06-30 | — | — | EP | claimed |
| WO-2003027069-A1 | PREPARATION AND USE OF PYRROLE DERIVATIVES FOR TREATING OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | claimed |