SCHEMBL6601786

SCHEMBL6601786

CN1CCN(NCc2csc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cc3)c2Cl)CC1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.77
F2 P00734 14/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6591243 0.87 F10 (1.00) F10F2
SCHEMBL6590564 0.82 F10 (0.71) F10F2
SCHEMBL6590705 0.81 F10 (1.00) F10F2
SCHEMBL6590613 0.81 F10 (0.87) F10F2
SCHEMBL6592963 0.81 F10 (0.77) F10F2
SCHEMBL6593184 0.81 F10 (0.77) F10F2
SCHEMBL6592085 0.80 F10 (0.78) F10F2
SCHEMBL6591493 0.80 F10 (0.69) F10F2
SCHEMBL6590345 0.80 F10 (1.00) F10F2
SCHEMBL6590528 0.79 F10 (1.00) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040108-B1 ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS SCHERING AG (DE) 2004-02-25 EP disclosed
US-6498185-B1 ENZYME FACTOR XA INHIBITORS BERLEX LABORATORIES, INC. 2002-12-24 US disclosed
US-6380221-B1 FOR THERAPY OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY BERLEX LABORATORIES, INC. 2002-04-30 US disclosed
US-6140351-A FOR TREATING THROMBOSIS BERLEX LABORATORIES, INC. (US) 2000-10-31 US disclosed