Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.45 |
| ▸ | FNTB | P49356 | 9/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757378 | 0.90 | FNTA (0.44) | FNTAFNTBCYP11B1CYP11B2LMNA | |
| SCHEMBL6757417 | 0.89 | FNTA (0.43) | FNTAFNTBCYP11B1CYP11B2LMNA | |
| SCHEMBL6755064 | 0.87 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2LMNA | |
| SCHEMBL6758247 | 0.86 | FNTA (0.59) | FNTAFNTBCYP11B1CYP11B2NAMPT | |
| SCHEMBL6602181 | 0.86 | FNTA (0.41) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL6756373 | 0.83 | FNTA (0.46) | FNTAFNTBCYP11B1CYP11B2NAMPT | |
| SCHEMBL6600844 | 0.82 | FNTA (0.45) | FNTAFNTBNAMPTPGGT1BSCN9A | |
| SCHEMBL6606446 | 0.82 | FNTA (0.45) | FNTAFNTBNAMPTPGGT1BSCN9A | |
| SCHEMBL6602018 | 0.81 | FNTA (0.41) | FNTAFNTBCYP11B1CYP11B2LMNA | |
| SCHEMBL6755058 | 0.79 | NAMPT (0.45) | FNTAFNTBCYP11B1CYP11B2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395581-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, PREPARATION AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2004-03-10 | — | — | EP | claimed |
| WO-2002098852-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2002-12-12 | — | — | WO | claimed |