Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511878 | 0.93 | POLB (0.42) | NR1I2TSHRNAAACYP1A2CYP3A4 | |
| SCHEMBL6414312 | 0.89 | TSHR (0.44) | NR1I2TSHRFAAHTRPV1CYP1A2 | |
| SCHEMBL6680917 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL21633771 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL7534046 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL23849703 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL21633686 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL21633712 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL11369217 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A | |
| SCHEMBL6681486 | 0.86 | NR1I2 (0.49) | NR1I2NAAACYSLTR2CYSLTR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923569-B1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0923569-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006711-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |