Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602534 | 0.85 | MC4R (0.64) | MC4RUSP2LMNAKMT2A | |
| SCHEMBL4525207 | 0.84 | MC4R (0.74) | MC4R | |
| SCHEMBL4677791 | 0.83 | MC4R (0.75) | MC4R | |
| SCHEMBL4510620 | 0.83 | MC4R (0.75) | MC4R | |
| SCHEMBL4514759 | 0.82 | MC4R (1.00) | MC4R | |
| SCHEMBL4530778 | 0.82 | MC4R (0.88) | MC4R | |
| SCHEMBL4529470 | 0.81 | MC4R (0.57) | MC4RKMT2A | |
| SCHEMBL4516829 | 0.81 | MC4R (0.82) | MC4R | |
| SCHEMBL4511840 | 0.80 | MC4R (1.00) | MC4R | |
| SCHEMBL4514793 | 0.80 | MC4R (1.00) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417190-A1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgen Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| WO-2003009850-A1 | SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC. (US) | 2003-02-06 | — | — | WO | claimed |