Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.60 |
| ▸ | PPARA | Q07869 | 13/20 | 0.60 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603216 | 0.93 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL6609370 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL27547897 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5173961 | 0.87 | PPARG (0.77) | PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL6276718 | 0.86 | PPARG (0.75) | PPARGPPARAPPARD | |
| Hydrochloric Acid SCHEMBL6276712 | 0.86 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL6606105 | 0.85 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL6603598 | 0.85 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL27568087 | 0.83 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL6608605 | 0.83 | PPARG (0.71) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102757-B1 | SUBSTITUTED OXAZOLE AND THIAZOLE DERIVATIVES AS HPPAR GAMMA AND HPPAR ALPHA ACTIVATORS | GLAXO GROUP LTD (GB) | 2004-04-14 | — | — | EP | disclosed |