Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27647148 | 0.90 | NPC1 (0.52) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL41312 | 0.89 | — | — | |
| SCHEMBL12614069 | 0.87 | — | — | |
| SCHEMBL29083650 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL28209085 | 0.87 | NPC1 (0.48) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL18170218 | 0.87 | — | — | |
| Bromide SCHEMBL31019391 | 0.87 | — | — | |
| Potassium SCHEMBL30612369 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL10511789 | 0.87 | — | — | |
| Phosphine SCHEMBL14798918 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023291-B1 | DIPYRIDOIMIDAZOLDERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO MCNEIL PHARM INC (US) | 2004-05-26 | — | — | EP | disclosed |
| US-5968946-A | FUSED PYRROLO-IMIDAZOPYRIDINE DERIVATIVES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-10-19 | — | — | US | disclosed |