Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718132 | 1.00 | GBA1 (0.43) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL8150738 | 0.85 | GBA1 (0.41) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL382015 | 0.83 | GBA1 (0.40) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL776553 | 0.83 | GBA1 (0.44) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL1148956 | 0.82 | GBA1 (0.38) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL28387150 | 0.81 | GBA1 (0.39) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL6701177 | 0.75 | — | — | |
| SCHEMBL23054278 | 0.74 | GBA1 (0.39) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL8699153 | 0.74 | SLC2A1 (0.41) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA | |
| SCHEMBL2256590 | 0.74 | GBA1 (0.39) | GBA1ALDH1A1SMN1; SMN2RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438060-B1 | ACTIVE METABOLITE OF A THROMBIN RECEPTOR ANTAGONIST | MERCK SHARP & DOHME (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-1218370-B1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-12-08 | — | — | EP | disclosed |
| EP-1218370-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | Aventis Pharma S.A. (FR) | 2002-07-03 | — | — | EP | disclosed |
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |
| WO-2001025227-A2 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-04-12 | — | — | WO | disclosed |