Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.80 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.60 |
| ▸ | PREP | P48147 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215391 | 1.00 | DPP4 (0.80) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL14587275 | 1.00 | DPP4 (0.80) | DPP4DPP8DPP9DPP7PREP | |
| Hydrochloric Acid SCHEMBL5641564 | 0.99 | DPP4 (0.79) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL5215339 | 0.90 | DPP4 (0.83) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL5215649 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| Hydrochloric Acid SCHEMBL5216724 | 0.89 | DPP4 (0.82) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL6605407 | 0.89 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| Hydrochloric Acid SCHEMBL5218591 | 0.88 | DPP4 (0.98) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL12921251 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL5218020 | 0.86 | DPP4 (0.76) | DPP4DPP8DPP9DPP7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-24 | — | — | EP | claimed |
| WO-2003002553-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-09 | — | — | WO | claimed |