Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.87 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.87 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.71 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734001 | 1.00 | PTGER4 (0.87) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734012 | 1.00 | PTGER4 (0.87) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734008 | 1.00 | PTGER4 (0.87) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734005 | 1.00 | PTGER4 (0.87) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734143 | 0.94 | PTGER4 (0.89) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734149 | 0.94 | PTGER4 (0.89) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734135 | 0.94 | PTGER4 (0.89) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5734147 | 0.94 | PTGER4 (0.89) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5733168 | 0.93 | PTGER4 (1.00) | PTGER4PTGER1PTGER2PTGER3 | |
| SCHEMBL5733158 | 0.93 | PTGER4 (1.00) | PTGER4PTGER1PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409455-A1 | PROSTAGLANDIN ANALOGUES-AS EP4 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008377-A1 | PROSTAGLANDIN ANALOGUES_AS EP4 RECEPTOR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-01-30 | — | — | WO | disclosed |