SCHEMBL660449

SCHEMBL660449

N[C@@H](Cc1ccc(O)cc1)C(=O)OP(=O)(O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.57
▸ TAAR1 Q96RJ0 3/20 0.44
▸ HDAC8 Q9BY41 2/20 0.44
▸ SLC6A2 P23975 1/20 0.44
▸ PTPRC P08575 1/20 0.43
▸ ESR1 P03372 2/20 0.43
▸ ESR2 Q92731 2/20 0.43
▸ PTPN1 P18031 1/20 0.42
▸ ANPEP P15144 2/20 0.41
▸ ERAP2 Q6P179 2/20 0.41
▸ ERAP1 Q9NZ08 2/20 0.41
▸ LAP3 P28838 1/20 0.41
▸ ENPEP Q07075 1/20 0.41
▸ DPP4 P27487 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL660450 1.00 SLC7A5 (0.57) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL20558572 0.98 SLC7A5 (0.56) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL28531036 0.98 SLC7A5 (0.56) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL28610929 0.98 SLC7A5 (0.56) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL29236051 0.95 SLC7A5 (0.53) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL660448 0.89 SLC7A5 (0.59) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL28984076 0.88 SLC7A5 (0.51) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL28274945 0.88 SLC7A5 (0.51) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL28770078 0.86 SLC7A5 (0.53) SLC7A5TAAR1HDAC8SLC6A2PTPRC
SCHEMBL28831601 0.86 SLC7A5 (0.56) SLC7A5TAAR1HDAC8SLC6A2PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105647824-A In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris 斯克利普斯研究院 2016-06-08 — — CN claimed
CN-105026422-A Sh2 domain variants UNIV WESTERN ONTARIO 2015-11-04 — — CN claimed
CN-102224238-B Non-natural amino acid replication-dependent microorganisms and vaccines AMBRX INC 2015-06-10 — — CN claimed
CN-101878303-B Directed evolution using proteins comprising unnatural amino acids SCRIPPS RESEARCH INST 2014-04-30 — — CN claimed
CN-102282174-B Antibodies against human epo receptor HOFFMANN LA ROCHE 2014-02-26 — — CN claimed
CN-103289960-A Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST 2013-09-11 — — CN claimed
CN-103215227-A Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST 2013-07-24 — — CN claimed
CN-103215228-A Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST 2013-07-24 — — CN claimed
CN-101223272-B Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST 2013-04-03 — — CN claimed
CN-102282174-A Antibodies against human epo receptor — 2011-12-14 — — CN claimed
CN-101939410-A In vivo unnatural amino acid expression in methylotrophic yeast Pichia pastoris SCRIPPS RESEARCH INST 2011-01-05 — — CN claimed
CN-101878303-A Directed evolution using proteins comprising unnatural amino acids SCRIPPS RESEARCH INST 2010-11-03 — — CN claimed
CN-101802214-A Generic kinase/phosphatase assay with single readout HOFFMANN LA ROCHE 2010-08-11 — — CN claimed
CN-101541955-A Hybrid suppressor tRNA for vertebrate cells AMBRX INC (US) 2009-09-23 — — CN claimed
CN-101511856-A Suppressor TRNA transcription in vertebrate cells AMBRX INC (US) 2009-08-19 — — CN claimed
CN-101223272-A Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST (US) 2008-07-16 — — CN claimed
CN-1306440-A Method for inhibiting off-flavors in oral compositions PROCTER & GAMBLE (US) 2001-08-01 — — CN claimed
CN-1300279-A Modulators of protein tyrosine phosphatases NOVO NORDISK AS (DK) 2001-06-20 — — CN claimed
CN-112972492-B Inhibition of cytokine-induced SH2 proteins in NK cells 沃尔特及伊莱萨霍尔医学研究院 2024-11-08 — — CN disclosed
CN-1043131-A Pentacyclic triterpene based compound as topoenzyme inhibitor or cytodifferentiation inductor RES TRIANGLE INST (US) 1990-06-20 — — CN disclosed
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