Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026688 | 1.00 | TACR1 (0.42) | TACR1CYP2D6HCRTR2SCN9ACFTR | |
| SCHEMBL6608982 | 0.88 | TACR1 (0.44) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL7026966 | 0.88 | TACR1 (0.44) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL6603700 | 0.88 | TACR1 (0.43) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL7033824 | 0.88 | TACR1 (0.43) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL6603330 | 0.87 | TACR1 (0.43) | TACR1CYP2D6HCRTR2SCN9ACFTR | |
| SCHEMBL6606866 | 0.86 | TACR1 (0.45) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL8664244 | 0.86 | TACR1 (0.45) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL7030644 | 0.85 | TACR1 (0.44) | TACR1CYP2D6HCRTR2CFTR | |
| SCHEMBL6606522 | 0.85 | TACR1 (0.44) | TACR1CYP2D6HCRTR2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175417-B1 | SUBSTITUTED BENZOLACTAM COMPOUNDS | PFIZER PROD INC (US) | 2004-01-07 | — | — | EP | disclosed |