Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.64 |
| ▸ | CTSD | P07339 | 3/20 | 0.64 |
| ▸ | BACE2 | Q9Y5Z0 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352134 | 0.89 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL6342366 | 0.88 | BACE1 (0.63) | BACE1CTSDBACE2 | |
| SCHEMBL6345930 | 0.88 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL6352146 | 0.88 | BACE1 (0.62) | BACE1CTSDBACE2 | |
| SCHEMBL6345858 | 0.88 | BACE1 (0.63) | BACE1CTSDBACE2 | |
| SCHEMBL6344834 | 0.87 | BACE1 (0.61) | BACE1CTSDBACE2 | |
| SCHEMBL6076417 | 0.86 | BACE1 (0.61) | BACE1CTSDBACE2 | |
| SCHEMBL6076424 | 0.86 | BACE1 (0.61) | BACE1CTSDBACE2 | |
| SCHEMBL8364584 | 0.86 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL6343737 | 0.86 | BACE1 (0.60) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395251-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-10 | — | — | EP | claimed |
| WO-2002100818-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |