Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.83 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774457 | 0.94 | LCK (0.72) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL5607542 | 0.91 | LCK (0.71) | LCKCHRNA7 | |
| SCHEMBL773400 | 0.91 | LCK (1.00) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL1540840 | 0.88 | LCK (0.72) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL772332 | 0.88 | LCK (1.00) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL774048 | 0.86 | LCK (0.92) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL774579 | 0.86 | LCK (0.92) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL774792 | 0.85 | LCK (0.78) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL774608 | 0.85 | LCK (1.00) | LCKCHRNA7ALDH1A1LMNAHTT | |
| SCHEMBL773486 | 0.85 | LCK (1.00) | LCKCHRNA7ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169038-A4 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-10-13 | — | — | EP | claimed |
| EP-1169038-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-09 | — | — | EP | claimed |
| WO-2000062778-A1 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB CO. (US) | 2000-10-26 | — | — | WO | claimed |