Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | F2 | P00734 | 4/20 | 0.76 |
| ▸ | F9 | P00740 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | PROC | P04070 | 1/20 | 0.60 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603986 | 0.95 | F10 (1.00) | F10F2F9PLAUPROC | |
| SCHEMBL6603523 | 0.94 | F10 (1.00) | F10F2F9PLAUPROC | |
| SCHEMBL7471581 | 0.93 | F10 (0.87) | F10F2F9PLAUPROC | |
| SCHEMBL6603294 | 0.92 | F10 (0.85) | F10F2F9PLAUPROC | |
| SCHEMBL6606132 | 0.92 | F10 (0.90) | F10F2F9PLAUPROC | |
| SCHEMBL6604247 | 0.91 | F10 (0.84) | F10F2F9PLAUPROC | |
| SCHEMBL6603360 | 0.90 | F10 (1.00) | F10F2F9PLAUPROC | |
| SCHEMBL6604675 | 0.89 | F10 (0.81) | F10F2F9PLAUPROC | |
| SCHEMBL6604006 | 0.88 | F10 (0.79) | F10F2F9PLAUPROC | |
| SCHEMBL6605707 | 0.88 | F10 (0.83) | F10F2F9PLAUPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196412-B1 | NITROGEN CONTAINING HETEROBICYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-06-09 | — | — | EP | claimed |
| CN-1454211-A | Nitrogen containing heterobicycles as factor xa inhibitors | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-11-05 | — | — | CN | claimed |
| EP-1196412-B1 | NITROGEN CONTAINING HETEROBICYCLES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-06-09 | — | — | EP | disclosed |
| CN-1454211-A | Nitrogen containing heterobicycles as factor xa inhibitors | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-11-05 | — | — | CN | disclosed |