SCHEMBL660499

SCHEMBL660499

N[C@H](Cc1cccc2ccccc12)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.59
MAPT P10636 2/20 0.56
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
MPO P05164 1/20 0.56
TSHR P16473 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
KMT2A Q03164 1/20 0.56
HIF1A Q16665 1/20 0.56
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1025267 1.00 CTNNB1 (0.59) CTNNB1MAPTKDM4EMEN1LMNA
SCHEMBL29397866 1.00 CTNNB1 (0.59) CTNNB1MAPTKDM4EMEN1LMNA
SCHEMBL29397858 1.00 CTNNB1 (0.59) CTNNB1MAPTKDM4EMEN1LMNA
SCHEMBL93515 1.00 CTNNB1 (0.59) CTNNB1MAPTKDM4EMEN1LMNA
SCHEMBL29482763 1.00 CTNNB1 (0.59) CTNNB1MAPTKDM4EMEN1LMNA
SCHEMBL93516 1.00 CTNNB1 (0.59) CTNNB1MAPTKDM4EMEN1LMNA
Hydrochloric Acid SCHEMBL29400669 0.98 CTNNB1 (0.58) CTNNB1MAPTKDM4EMEN1LMNA
Hydrochloric Acid SCHEMBL5967395 0.98 CTNNB1 (0.58) CTNNB1MAPTKDM4EMEN1LMNA
Hydrochloric Acid SCHEMBL29370597 0.98 CTNNB1 (0.58) CTNNB1MAPTKDM4EMEN1LMNA
Hydrochloric Acid SCHEMBL30030000 0.98 CTNNB1 (0.58) CTNNB1MAPTKDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730969-A Beta-lapachone-amino acid conjugate, and preparation method and application thereof 中国药科大学 2023-09-12 CN claimed
CN-106117253-B Supermolecule complex synthesized by cucurbituril and amino acid, preparation method and application 贵州大学 2019-02-19 CN claimed
EP-2748183-B1 POTENT LIGANDS OF THE GHRELIN RECEPTOR UNIV LEIPZIG (DE) 2018-12-26 EP claimed
CN-108187077-A 64PSMA targeted inhibition agent of Cu labels and preparation method and application 北京肿瘤医院 2018-06-22 CN claimed
US-9718861-B2 Potent ligands of the ghrelin receptor UNIVERSITAET LEIPZIG (DE) 2017-08-01 US claimed
EP-3071177-B1 TARGETED CAPSULES FOR THE DELIVERY OF SKIN WHITENING AGENTS IN THE SKIN INFINITEC ACTIVOS S L (ES) 2017-05-10 EP claimed
EP-3071177-A2 TARGETED CAPSULES FOR THE DELIVERY OF SKIN WHITENING AGENTS IN THE SKIN Infinitec Activos S.L. (ES) 2016-09-28 EP claimed
US-20160250128-A1 TARGETED CAPSULES FOR THE DELIVERY OF SKIN WHITENING AGENTS IN THE SKIN INFINITEC ACTIVOS S.L. (ES) 2016-09-01 US claimed
US-20160022636-A1 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2016-01-28 US claimed
EP-2968240-A2 PHYSIOLOGICAL LIGANDS FOR GPR139 Janssen Pharmaceutica, N.V. (BE) 2016-01-20 EP claimed
EP-0417165-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. EASTMAN KODAK CO (US) 1991-03-20 EP claimed
WO-1991001144-A1 LABELED POLYPEPTIDE DERIVATIVES SANDOZ LTD (CH) 1991-02-07 WO claimed
EP-0400051-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY. EASTMAN KODAK CO (US) 1990-12-05 EP claimed
WO-1989010933-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1989-11-16 WO claimed
WO-1989007110-A1 POLYPEPTIDE COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY EASTMAN KODAK COMPANY (US) 1989-08-10 WO claimed
WO-1988002756-A2 PEPTIDE DERIVATIVES SANDOZ AG (CH) 1988-04-21 WO claimed
EP-0215171-A2 Peptides THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1987-03-25 EP claimed
EP-0214872-A2 Somatostatin analoge The Administrators of The Tulane Educational Fund (US) 1987-03-18 EP claimed
EP-0171477-A2 Amino acid-containing therapeutic compounds THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) 1986-02-19 EP claimed
US-4409208-A PEPTIDES WHICH INHIBIT GONADOTROPINS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1983-10-11 US claimed