Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958987 | 0.86 | MIF (0.59) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL2961677 | 0.86 | MIF (0.59) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL6605434 | 0.86 | MIF (0.59) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL13199874 | 0.86 | MIF (0.59) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL2956930 | 0.84 | MIF (0.54) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL13199890 | 0.84 | MIF (0.57) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL5015281 | 0.83 | MIF (0.56) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL2959069 | 0.83 | MIF (0.56) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL2962191 | 0.83 | MIF (0.56) | MIFGABRA1ALDH1A1NPC1RAB9A | |
| SCHEMBL2956533 | 0.82 | MIF (0.54) | MIFGABRA1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424336-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |