Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605781 | 1.00 | CNR2 (0.43) | CNR2PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6606590 | 0.86 | MAPT (0.37) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6606599 | 0.86 | MAPT (0.37) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6605677 | 0.85 | MAPT (0.37) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6605671 | 0.85 | MAPT (0.37) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6605284 | 0.84 | PDE4A (0.44) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6605061 | 0.84 | MAPT (0.36) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6605063 | 0.84 | MAPT (0.36) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6605292 | 0.84 | PDE4A (0.44) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6607113 | 0.83 | MAPT (0.41) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |