Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605901 | 1.00 | HPGD (0.37) | HPGDCHEK1CYP4F2CYP4A11KMT2A | |
| SCHEMBL6611068 | 0.84 | HPGD (0.40) | HPGDCHEK1CYP4F2CYP4A11KMT2A | |
| SCHEMBL6611074 | 0.84 | HPGD (0.40) | HPGDCHEK1CYP4F2CYP4A11KMT2A | |
| SCHEMBL6610774 | 0.83 | RECQL (0.36) | KDM4ERECQLSMN1; SMN2HIF1AEGFR | |
| SCHEMBL6610767 | 0.83 | RECQL (0.36) | KDM4ERECQLSMN1; SMN2HIF1AEGFR | |
| SCHEMBL6610815 | 0.82 | SMN1; SMN2 (0.35) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL6610811 | 0.82 | SMN1; SMN2 (0.35) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL6606234 | 0.82 | PDE4D (0.43) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL6606241 | 0.82 | PDE4D (0.43) | KMT2AKDM4EMEN1RECQLSMN1; SMN2 | |
| SCHEMBL6605347 | 0.82 | CYP11B1 (0.40) | HPGDKMT2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |