Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.83 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.70 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863522 | 0.91 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL4855124 | 0.91 | MAPK14 (0.85) | MAPK14MAPK11 | |
| SCHEMBL4858295 | 0.90 | MAPK14 (0.83) | MAPK14MAPK11 | |
| SCHEMBL4856613 | 0.90 | MAPK14 (0.83) | MAPK14MAPK11 | |
| SCHEMBL4859664 | 0.89 | MAPK14 (0.79) | MAPK14MAPK11 | |
| SCHEMBL4863066 | 0.89 | MAPK14 (0.81) | MAPK14MAPK11 | |
| Gw708893X SCHEMBL4856407 | 0.89 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL4859745 | 0.89 | MAPK14 (0.81) | MAPK14MAPK11 | |
| Gw701032X SCHEMBL4857321 | 0.87 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL4863540 | 0.87 | MAPK14 (0.79) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436269-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033482-A1 | OXADIAZOLYL-BIPHENYLCARBOXAMIDES AND THEIR USE AS P38 KINASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-04-24 | — | — | WO | disclosed |