Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604354 | 0.96 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL7724658 | 0.91 | KCNH2 (0.47) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL7724654 | 0.91 | KCNH2 (0.47) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL7731037 | 0.90 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL6604185 | 0.89 | KCNH2 (0.43) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL6604527 | 0.88 | KCNH2 (0.44) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL7725928 | 0.88 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL6609758 | 0.88 | KCNH2 (0.43) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL6605618 | 0.87 | KCNH2 (0.43) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL6603923 | 0.87 | KCNH2 (0.45) | KCNH2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218370-B1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-12-08 | — | — | EP | disclosed |
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |