Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.57 |
| ▸ | ESR1 | P03372 | 8/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450850 | 0.99 | F2 (0.58) | F2ESR1ESR2ITGA4LTA4H | |
| SCHEMBL6605492 | 0.95 | F2 (0.53) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7452480 | 0.94 | F2 (0.53) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6606509 | 0.92 | F2 (0.57) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6606711 | 0.90 | ESR1 (0.60) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6605496 | 0.87 | F2 (0.53) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6604504 | 0.86 | F2 (0.58) | F2ESR1ESR2ITGA4LTA4H | |
| SCHEMBL7983860 | 0.86 | F2 (0.53) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6606766 | 0.85 | ESR1 (0.55) | F2ESR1ESR2ITGA4 | |
| Oxalic Acid SCHEMBL6609726 | 0.85 | ESR1 (0.53) | F2ESR1ESR2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244655-B1 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-02-18 | — | — | EP | disclosed |
| US-6620837-B1 | 1-Benzothiophene derivatives | ELI LILLY AND COMPANY | 2003-09-16 | — | — | US | disclosed |