Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | DHFR | P00374 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831800 | 0.92 | MEN1 (0.85) | MEN1KMT2ANPC1RAB9ADHFR | |
| Hydrochloric Acid SCHEMBL11843324 | 0.89 | KMT2A (0.80) | MEN1KMT2ANPC1RAB9ADHFR | |
| Hydrochloric Acid SCHEMBL11833810 | 0.81 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL17985055 | 0.81 | KMT2A (0.67) | MEN1KMT2ANPC1RAB9ADHFR | |
| Hydrochloric Acid SCHEMBL11842546 | 0.79 | MEN1 (0.65) | MEN1KMT2ANPC1RAB9AFAAH | |
| SCHEMBL18550404 | 0.78 | KMT2A (0.64) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL29883119 | 0.77 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL1038680 | 0.77 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9ADHFR | |
| Hydrochloric Acid SCHEMBL31647890 | 0.76 | MEN1 (0.62) | MEN1KMT2ANPC1RAB9ADHFR | |
| SCHEMBL16220609 | 0.76 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997462-B1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | NIPPON KAYAKU KK (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-6294547-B1 | Naphthyridine deratives or salts thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0997462-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES OR SALTS THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |